Yale Cancer Biology Institute

Meet the labs of the Yale Cancer Biology Institute

• Alarcón Lab

  Uncovering the physiological and pathophysiological roles of RNA modifications at the molecular, cellular, and organism level through multidisciplinary approaches

  

• Ferguson Lab

  Defining therapeutic opportunities with growth factor receptors using structure

  

• Kabeche Lab

  Understanding the interplay between chromosomal instability and DNA damage response defects in cancers to uncover new cancer therapy targets

  

• Klein Lab

  Deciphering the structural underpinnings of oncogene activation to inform the rational design of antibody therapeutics

  

• LaMarche Lab

  We combine high-dimensional profiling of cancer patient tissues with detailed mechanistic studies in mouse models to develop new immunotherapies for solid tumors

  

• Lemmon Lab

  Understanding receptor tyrosine kinase signaling and how to correct aberrant activity when altered in diseases such as cancer

  

• Liu Lab

  Studying proteomics, protein turnover, and post-translational modifications to understand cancer aneuploidy, cellular signaling transduction, and biodiversity

  

• Muzumdar Lab

  Deciphering how genetic alterations interact with environmental and host factors to drive cancer development

  

• Schlessinger Lab

  Analyzing the mode of action of growth factor receptors and the intracellular signaling pathways that activated in response to growth factor stimulation