Yale Cancer Biology Institute Publications 2024

Sogunro, A., Muzumdar, M. (2024) Keep It Moving: Physical Activity in the Prevention of Obesity-Driven Pancreatic Cancer. Cancer Research. doi: 10.1158/0008-5472.CAN-24-1474. PMID: 39279380

Wang, S., Di, Y., Yang, Y., Salovska, B., Li, W., Hu, L., Yin, J., Shao, W., Zhou, D., Cheng, J., Liu, D., Yang, H., Liu, Y. (2024) PTMoreR-enabled cross-species PTM mapping and comparative phosphoproteomics across mammals. Cell Reports Methods. doi: 10.1016/j.crmeth.2024.100859. PMID: 39255793

Mühlenbeck, H., Tsutsui, Y., Lemmon, M., Bender, K., Zipfel, C. (2024) Allosteric activation of the co-receptor BAK1 by the EFR receptor kinase initiates immune signaling. Elife.  doi: 10.7554/eLife.92110. PMID: 39028038

Edman, N., Phal, A., Redler, R., Schlichthaerle, T., Srivatsan, S., Ehnes, D., Etemadi, A., An, S., Favor, A., Li, Z., Praetorius, F., Gordon, M., Vincent, T., Marchiano, S., Blakely, L., Lin, C., Yang, W., Coventry, B., Hicks, D., Cao, L., Bethel, N., Heine, P., Murray, A., Gerben, S., Carter, L., Miranda, M., Negahdari, B., Lee, S., Trapnell, C., Zheng, Y., Murry, C., Schweppe, D., Freedman, B., Stewart, L., Ekiert, D., Schlessinger, J., Shendure, J., Bhabha, G., Ruohola-Baker, H., Baker, D. (2024) Modulation of FGF pathway signaling and vascular differentiation using designed oligomeric assemblies. Cell. doi: 10.1016/j.cell.2024.05.025. PMID: 38861993

Bagchi, A., Stayrook, S., Xenaki, K., Starbird, C., Doulkeridou, S., El Khoulati, R., Roovers, R., Schmitz, K., van Bergen En Henegouwen, P., Ferguson, K. (2024) Structural insights into the role and targeting of EGFRvIII. Structure. doi: 10.1016/j.str.2024.05.018. PMID: 38908376

Cecchini, M., Salem, R., Robert, M., Czerniak, S., Blaha, O., Zelterman, D., Rajaei, M., Townsend, J., Cai, G., Chowdhury, S., Yugawa, D., Tseng, R., Mejia Arbelaez, C., Jiao, J., Shroyer, K., Thumar, J., Kortmansky, J., Zaheer, W., Fischbach, N., Persico, J., Stein, S., Khan, S., Cha, C., Billingsley, K., Kunstman, J., Johung, K., Wiess, C., Muzumdar, M., Spickard, E., Aushev, V., Laliotis, G., Jurdi, A., Liu, M., Escobar-Hoyos, L., Lacy, J. (2024) Perioperative Modified FOLFIRINOX for Resectable Pancreatic Cancer: A Nonrandomized Controlled Trial. JAMA Oncology. doi: 10.1001/jamaoncol.2024.1575. PMID: 38900452 

Rosenberger, G., Li, W., Turunen, M., He, J., Subramaniam, P.S., Pampou, S., Griffin, A.T., Karan, C., Kerwin, P., Murray, D., Honig, B., Liu, Y., Califano, A. (2024) Network-based elucidation of colon cancer drug resistance mechanisms by phosphoproteomic time-series analysis. Nature Communications. doi: 10.1038/s41467-024-47957-3. PMID: 38724493

Gui, Y., Fu, H., Palanza, Z., Tao, J., Lin, Y.H., Min, W., Qiao, Y., Bonin, C., Hargis, G., Wang, Y., Yang, P., Kreutzer, D.L., Wang, Y., Liu, Y., Yu, Y., Liu, Y., Zhou, D.. (2024) Fibroblast expression of transmembrane protein smoothened governs microenvironment characteristics after acute kidney injury. The Journal of Clinical Investigation. doi: 10.1172/JCI165836. PMID: 38713523 

Ke, S., Dang, F., Wang, L., Chen, J.Y., Naik, M.T., Li, W., Thavamani, A., Kim, N., Naik, N.M., Sui, H., Tang, W., Qiu, C., Koikawa, K., Batalini, F., Stern Gatof, E., Isaza, D.A., Patel, J.M., Wang, X., Clohessy, J.G., Heng,Y.J., Lahav, G., Liu, Y., Gray, N.S., Zhou, X.Z., Wei, W., Wulf, G.M., Lu, K.P.. (2024) Reciprocal antagonism of PIN1-APC/CCDH1 governs mitotic protein stability and cell cycle entry.

Nature Communications. doi: 10.1038/s41467-024-47427-w. PMID: 38622115

Bellone, S., Jeong, K., Halle, M.K., Krakstad, C., McNamara, B., Greenman, M., Mutlu, L., Demirkiran, C., Hartwich, T.M.P., Yang-Hartwich, Y., Zipponi, M., Buza, N., Hui, P., Raspagliesi, F., Lopez, S., Paolini, B., Milione, M., Perrone, E., Scambia, G., Altwerger, G., Ravaggi, A., Bignotti, E., Huang, G.S., Andikyan, V., Clark, M., Ratner, E., Azodi, M., Schwartz, P.E., Quick, C.M., Angioli, R., Terranova, C., Zaidi, S., Nandi, S., Alexandrov, L.B., Siegel, E.R., Choi, J., Schlessinger, J., Santin, A.D. (2024) Integrated mutational landscape analysis of poorly differentiated high-grade neuroendocrine carcinoma of the uterine cervix. Proc Natl Acad Sci USA. doi:10.1073/pnas.2321898121. PMID: 38625939

Hu, Z., Chen, PH., Li, W., Krone, M., Zheng, S., Saarbach, J., Velasco, IU., Hines, J., Liu, Y., Crews, CM. (2024) EGFR targeting PhosTACs as a dual inhibitory approach reveals differential downstream signaling. Science Advances. doi: 10.1126/sciadv.adj7251 PMID: 38536914 

Luan, Y., Hu, J., Wang, Q., Wang, X., Li, W., Qu, R., Yang, C., Rajendran, BK., Zhou, H., Liu, P., Zhang, N., Shi, Y., Liu, Y., Tang, W., Lu, J., Wu, D. (2024) Wnt5 controls splenic myelopoiesis and neutrophil functional ambivalency during DSS-induced colitis. Cell Reports.  doi: 10.1016/j.celrep.2024.113934. PMID: 38461416

Liao, X., Li, W., Zhou, H., Rajendran, B., Li, A., Ren, J., Luan, Y., Calderwood, D., Turk, B., Tang, W., Liu, Y., Wu, D. (2024) The CUL5 E3 ligase complex negatively regulates central signaling pathways in CD8+ T cells. Nature Communications. doi: 10.1038/s41467-024-44885-0. PMID: 38242867 

Liu, Q., Zhang, J., Guo, C., Wang, M., Wang, C., Yan, Y., Sun, L., Wang, D., Zhang, L., Yu, H., Hou, L., Wu, C., Zhu, Y., Jiang, G., Zhu, H., Zhou, Y., Fang, S., Zhang, T., Hu, L., Li, J., Liu, Y., Zhang, H., Zhang, B., Ding, L., Robles, AI., Rodriguez, H., Gao, D., Ji, H., Zhou, H., Zhang, P. (2024) Proteogenomic characterization of small cell lung cancer identifies biological insights and subtype-specific therapeutic strategies. Cell. doi: 10.1016/j.cell.2023.12.004. PMID: 38181741

Huang, X., Gan, Z., Cui, H., Lan, T., Liu, Y., Caron, E., Shao, W. (2024) The SysteMHC Atlas v2.0, an updated resource for mass spectrometry-based immunopeptidomics. Nucleic Acids Research. doi: 10.1093/nar/gkad1068. PMID: 38000392 

Mudumbi, K., Burns, E., Schodt, D., Petrova, Z., Kiyatkin, A., Kim, L., Mangiacapre, E., Ortiz-Caraveo, I., Rivera Ortiz, H., Hu, C., Ashtekar, K., Lidke, K., Lidke, D., Lemmon, M. (2024) Distinct interactions stabilize EGFR dimers and higher-order oligomers in cell membranes. Cell Reports. doi: 10.1016/j.celrep.2023.113603. PMID: 38117650

Walker, G., Brown, C., Ge, X., Kumar, S., Muzumdar, M., Gupta, K., Bhattacharyya, M. (2024) Oligomeric organization of membrane proteins from native membranes at nanoscale spatial and single-molecule resolution. Nature Nanotechnology. doi: 10.1038/s41565-023-01547-4. PMID: 38012273